Mitochondrial transporters are involved in the exchange of metabolites and intermediates between the mitochondria and the cell cytoplasm. Due to their known role in maintaining mitochondrial homeostasis and in plant response to environmental stress, these carriers are potential targets to improve plant performance under adverse conditions. This presentation will focus on the physiological and metabolic roles played by Uncoupling Mitochondrial Protein (UCP) and Dicarboxylate Carrier (DIC). The recent discovery that UCP1 is involved in the mitochondrial control of a hypoxia response via stabilization of Group VII Ethylene Response Factor Transcription Factors (ERFVIIs) through the PRT6 N-Degron pathway will be discussed. In parallel, the molecular and functional characterization of single and double T-DNA insertion mutants of DIC genes in Arabidopsis will be presented.
Seminar in english.